Vetoquinol Imidospot (Imidacloprid 10% + Moxidectin 2.5%) Tick and Flea Spot On for Dogs

Most flea and tick treatments stop at the coat. Imidospot goes further — one monthly pipette that handles everything living on your dog and everything living inside them.

Vetoquinol Imidospot spot on for dogs is a dual-action monthly ectoparasiticide and endoparasiticide that combines Imidacloprid 10% w/v and Moxidectin 2.5% w/v in a single spot-on application. Imidacloprid kills adult fleas on contact within 4 hours — one of the fastest flea knock-down rates among spot-on treatments available in India. Moxidectin absorbs into the bloodstream and simultaneously treats internal parasites, including heartworm larvae, hookworms, roundworms, and whipworms, while also covering sarcoptic mange and demodicosis.

The result is one of the most complete monthly parasite protection protocols available for dogs in India — no separate dewormer, no separate mange treatment, no separate heartworm prevention. Available in two sizes: 2.5ml for dogs 10 to 25kg and 4ml for dogs 25 to 40kg.

(From Vetoquinol India Animal Health Pvt. Ltd., Bhiwandi, Thane — the Indian arm of Vetoquinol S.A., a global veterinary pharmaceutical company. Safe for dogs and puppies from 7 weeks of age. Schedule H medicine.)

What Does Vetoquinol Imidospot Spot On Treat in Dogs?

Here is what Imidospot imidacloprid moxidectin spot-on treats and prevents:

• Flea treatment and prevention — Imidacloprid kills adult fleas within 4 hours of application, one of the fastest onset times among spot-on treatments. It spreads across the coat through the sebaceous glands providing full body coverage and continuous protection for up to 4 weeks

• Tick control — kills ticks that attach to your dog during walks, outdoor activity, or contact with other animals. Monthly application provides residual protection against reinfestation

• Lice control — eliminates sucking and biting lice that cause coat damage and skin irritation in dogs

• Sarcoptic mange treatment — treats Sarcoptes scabiei infestations responsible for intense itching, crusty skin, and fur loss in dogs — one of the most common and distressing skin conditions in Indian dogs

• Demodicosis treatment — also effective against Demodex mites, making Imidospot one of the few monthly spot-ons with confirmed activity against both sarcoptic and demodectic mange

• Heartworm prevention — Moxidectin prevents heartworm disease caused by Dirofilaria immitis larvae, providing monthly protection against a potentially fatal condition increasingly relevant in India's high-mosquito-density urban environments

Hookworm, roundworm, and whipworm treatment — the Moxidectin component provides internal parasite coverage simultaneously, eliminating the need for a separate oral dewormer alongside external parasite control

How Does Imidacloprid Plus Moxidectin Work?

• Imidospot works through two active ingredients targeting completely different categories of parasites through different mechanisms

• Imidacloprid is a neonicotinoid insecticide that spreads across the skin and coat after application, attacking the nervous system of fleas, ticks, and lice on contact by binding to nicotinic acetylcholine receptors — causing paralysis and death within hours

• Moxidectin is a macrocyclic lactone that is absorbed through the skin into the bloodstream, where it reaches internal parasites, including heartworm larvae, hookworms, roundworms, and whipworms — binding to glutamate-gated chloride channels in parasite nerve and muscle cells, causing paralysis and death

• Moxidectin also reaches Sarcoptes and Demodex mites through the systemic route, making it effective against both types of mange without requiring a separate treatment

• Together, this dual-action spot-on for dogs delivers complete internal and external parasite protection in a single monthly application

• Imidacloprid's 4-hour flea kill onset is significantly faster than many competing spot-on combinations, providing rapid relief for dogs in active infestations

Which Size of Imidospot Should You Buy for Your Dog?

Two sizes are available. Weigh your dog before every order:

 

 

Note: Imidospot is currently available in sizes starting from 10kg. If your dog weighs below 10kg, consult your vet for an appropriately dosed alternative.

How Do You Apply Imidospot Spot On to Your Dog?

1. Select the correct pipette size for your dog's bodyweight — always weigh before selecting

2. Part the fur at the base of the neck, between the shoulder blades, until the skin is clearly visible

3. Place the tip of the pipette directly on the skin and squeeze the entire contents in one spot

4. For larger dogs using the 4ml pipette, apply across 2 to 3 spots along the spine for better distribution

5. Do not rub in — allow the solution to spread naturally through the coat via the sebaceous glands

6. Keep your dog dry and avoid bathing for at least 48 hours after application

7. Apply once every month for continuous protection

If you want a video-guide on how to apply the spot-on for your dog, then watch this: Spot on Dog

⚠️ Before you use it:

• For dogs and puppies 7 weeks of age and older only

• Apply only where your dog cannot lick — the back of the neck or along the spine

• Wash your hands thoroughly after application

• Keep children and other pets away from the treated coat until fully dry

• Do not bathe your dog for 48 hours before or after application

• Schedule H medicine — keep out of reach of children

What Are the Side Effects of Imidospot Spot On?

Side effects are uncommon when applied correctly. Here is what to watch for:

• Temporary skin irritation at the application site — mild redness, itching, or localised hair loss at the spot where the pipette was applied. Usually resolves within a few days without treatment

• Greasy or clumped fur at the application site — the pipette solution may leave a slightly oily patch for 24 to 48 hours after application. This is normal and not a sign of a reaction

• Lethargy or drooling — rare, and typically occurs only if the dog manages to lick the application site before it has fully dried. Apply to the back of the neck, where your dog cannot reach, and keep children away from the treated area until dry

• Neurological signs — extremely rare, but if your dog shows tremors, loss of coordination, or severe lethargy after application, contact your vet immediately

When Should You Not Use Imidospot Spot On?

Check with your vet before using if:

• Your puppy is under 7 weeks of age

• Your dog is pregnant or nursing — consult your vet before use in breeding animals

• Your dog is unwell or underweight — apply only to healthy animals

• Your dog is already on another antiparasitic treatment — check for interactions before combining

• Your dog is a Collie, Shetland Sheepdog, Australian Shepherd, or related herding breed — these breeds can carry the MDR1/ABCB1 gene mutation that increases sensitivity to macrocyclic lactones, including Moxidectin. Always consult your vet before first use in any herding breed

⚠️ Clinical Safety Notice:

• Imidospot is a Schedule H medicine — it requires a valid prescription

• MDR1-sensitive herding breeds require vet consultation before use. Unlike Selamectin, Moxidectin carries a real risk of toxicity in MDR1/ABCB1 gene-mutant breeds at therapeutic doses — do not apply without vet clearance if your dog is a Collie, Sheltie, Australian Shepherd, or Border Collie

• Apply only to the back of the neck or along the spine, where your dog cannot lick — licking before the application site dries is the most common cause of adverse reactions

• In multi-pet households, keep your dog separated from other pets until the application site is completely dry

• Keep your dog dry for 48 hours after application — bathing too soon significantly reduces efficacy

How Should You Store Imidospot Spot On?

• Store at room temperature, away from direct sunlight

• Keep in original packaging until use

• Keep out of reach of children and other pets

• Do not freeze

• Check the expiry date on the packaging before use

What Are the Alternatives to Vetoquinol Imidospot?

Always consult your vet before switching antiparasitic treatments, particularly if your dog is on a heartworm prevention protocol or is a herding breed.

Vet Also Recommends

• Explore our collection of Dog Tick & Flea Grooming Solutions

• Explore our collection of Dog Tick & Flea Remedies

• Explore our complete collection of Cat Tick & Flea Remedies

Keep your dog protected inside and out — buy Vetoquinol Imidospot spot on for dogs online on Supertails. 100% authentic, sourced from authorised distributors. Check Imidospot price across both sizes and read reviews from verified buyers on the product page. Same-day delivery available in select cities. Not sure which size is right or whether Imidospot is safe for your breed? Chat with our in-house vets before you order.

FAQs

What does Vetoquinol Imidospot spot on treat in dogs?

Vetoquinol Imidospot is a dual-action monthly spot-on that kills fleas within 4 hours, controls ticks and lice, treats sarcoptic mange and demodicosis, prevents heartworm, and treats hookworm, roundworm, and whipworm simultaneously. It contains Imidacloprid 10% for external parasites and Moxidectin 2.5% for internal parasites, eliminating the need for a separate dewormer or mange treatment alongside monthly flea control.

How do I apply Imidospot spot-on to my dog correctly?

Part the fur at the base of the neck between the shoulder blades until the skin is visible. Apply the entire pipette contents directly onto the skin — in one spot for smaller dogs, across 2 to 3 spots along the spine for larger dogs, using the 4ml pipette. Do not rub in. Keep the site dry for 48 hours and avoid bathing before and after application. Apply once every month.

Which size of Imidospot should I buy for my dog?

Imidospot comes in two sizes: 2.5ml for dogs weighing 10 to 25kg, and 4ml for dogs weighing 25 to 40kg. Always weigh your dog before ordering — never estimate. If your dog falls below 10kg or above 40kg, consult your vet for an appropriately dosed alternative. Using the wrong pipette size risks underdosing, which reduces efficacy, or overdosing, which increases the risk of side effects.

Is Imidospot safe for all dog breeds, including Collies?

Imidospot contains Moxidectin, a macrocyclic lactone that can cause toxicity in dogs carrying the MDR1/ABCB1 gene mutation — common in Collies, Shelties, Australian Shepherds, and Border Collies. Unlike Selamectin, Moxidectin carries a genuine risk in these breeds at therapeutic doses. Always consult your vet before using Imidospot on any herding breed, and consider Selamectin-based alternatives if MDR1 status is unknown.

What is the difference between Imidospot and Advocate for dogs?

Both contain identical active ingredients at identical concentrations — Imidacloprid 10% and Moxidectin 2.5% — and provide the same broad spectrum internal and external parasite coverage. The primary differences are brand and manufacturer. Advocate is from Elanco (formerly Bayer), one of the largest global veterinary pharmaceutical companies. Imidospot is from Vetoquinol, a French veterinary pharmaceutical company with a strong presence in India. Coverage, efficacy, and safety profiles are equivalent.